Mizrahi was born in Brooklyn, New York of Egyptian Jewish heritage. He is the cousin of rock guitarist Sylvain Sylvain, former player in the New York Dolls.

When Isaac was eight, his family moved to the middle-class Midwood section of Brooklyn. He contracted spinal meningitis during this time and his confinement was spent eating junk food and viewing television, especially old movies. The 1961 remake of Back Street, about an affair between a fashion designer and a married man, was a pivotal event in Mizrahi's development. The glamour of the fashion industry depicted in the movie became an inspiration to him to design clothes. When Isaac was 10 years old, Zeke Mizrahi bought a sewing machine for him. Isaac set up a workroom in the basement and created clothes for puppets for neighborhood birthday parties. At 13, Isaac was designing clothes for himself, his mother, and a close friend of his mother, Sarah Haddad.

His earliest design influences stemmed from his his mother's all-American wardrobe, which included clothing from Halston, Geoffrey Beene, Claire McCardell and Norman Norell.

1982 Graduated from Parsons School of Design, New York. Worked for Perry Ellis, and said he was a major influence who taught him how to cut a dress, and many lessons in life. After this, he worked with Jeff Banks and Calvin Klein.

After leaving Calvin Klein, in June 1987 he and Sarah Haddad-Cheney pooled $50,000 each and opened Mizrahi's own womenswear company. They occupied a loft on Greene Street in SoHo. Seven stores bought the first season's collection. By the first collection show in April 1988 Haddad-Cheney had secured additional financing from the owners of Gitano Jeans company. In 1990 the company's workrooms and showroom moved to an expanded space on Wooster Street. Mizrahi's menswear collection premiered in April 1990.

1990 Isaac Mizrahi is presented with the CFDA designer of the year award for his women's wear collection.

The year 1997 proved to be a milestone in Mizrahi's career. He announced an unprecedented deal with three major Asian markets in Japan, Singapore, and Korea which included freestanding stores, in-store shops, wholesale distribution, manufacturing, and sublicenses in Japan and shops and distribution in Southeast Asia, an online ABC source reported. The deal was estimated to generate at least $150 million in retail sales by the year 2000.

Mizrahi has made appearances in numerous television shows and movies since the 1990s. In 1995, a movie was released about the development of his Fall 1994 collection called Unzipped made by his freind Douglas Keeve. In fall 2005 the Isaac show debuted on Style Network. He previously had a show on the Oxygen network. His new less-expensive line ISAAC, opens in 34 locations around the USA. Each boutique will show his new logo, a Silver Star.

He often appears on many of E!'s programs and has become well-known for being flamboyant and considered by some to be rude. He also appeared as himself in the episode "Plus One is the Loneliest Number" of the fifth season of Sex and the City.

He also guest starred on the American dramedy series Ugly Betty, in which he played a reporter for the cable channel Fashion TV in the episode "Lose the Boss".

Mizrahi also appeared as himself in The Apprentice season 1 (episode 6) as one of the celebrities auction for The Elizabeth Glaser Pediatric AIDS Foundation.

He made a series of comic books called Sandee, the Adventures of a Supermodel, published by Simon & Schuster.

Mizrahi is currently the spokesperson for Klein-Becker's StriVectin anti-wrinkle cream.

He is developing "The Collection," a one-hour scripted project that draws on the experiences of the designer for The CW Network.

Known for his magnetic personality and witty style, Mizrahi has won four Council of Fashion Designers of America (CFDA) awards. He is famous for his use of colour and the clean flattering lines of his designs.

Chanel, who was financing him, pulled the plug and Isaac had closed his own fashion house in 1998. He started his own TV show interviewing celebrities.

However in February 2003, Mizrahi entered into a new partnership with New York based Hip retailer TARGET. Isaac created an exclusive collection of classically designed fashion sportswear and accessories for style conscious women. The collections are named "Isaac Mizrahi for Target" and he unveiled his debut collection in April 2003 in Minneapolis at the Walker Arts Center. Target is putting the designer back on the fashion map in a major mass-market way.

Mizrahi's television show will be featured in the advertising and marketing campaign for this new line.

When he was interviewed in September, Isaac said he was very happy working with Target. Certain aspects of the couture scene and the constant rush to try and make money, just made him unhappy. Now he is making clothes for ordinary Americans at reasonable prices, and they are "racy, fun and crazy" and very popular.

But Isaac's heart has always been with fashion shows, and in June 2004 he put on his first show in six years, and it was really successful. The show celebrates Bergdorf Goodman's decision to devote space in its American couture collections for Mizrahi's label. The designs can also be seen on www.target.com

The Look

It is as if Mizrahi was challenged by distilling the most well-bred form of each garment to an understated glamor, whether tartan taken to a sensuous evening gown but still buckled as if Balmoral livery; pocketbooks and luggage ingeniously incorporated into clothing with the practical pocket panache of McCardell; or versions of high style in adaptations of men's bathrobes or sweatshirting used for evening. While Mizrahi was often commended for the youthfulness of his clothing, the praise was for the freshness of his perception, his ability to recalculate a classic, not just a market for young women. His interest in the Empire waistline; his practicality of wardrobe separates in combination; and his leaps between day and evening addressed all women equally. Mizrahi had clearly demonstrated the range of a commercially viable designer while at the same time demonstrating his simplifying glamor and the cool nonchalant charm of his smart (intellectually and aesthetically) clothing. Mizrahi had referred to his style as a "classic New York look," which presumably meant a casual American idiom, but inflected with big-city reserve and refinement. Mizrahi captured something of Manhattan chic and glamor of the 1940s and 1950s. His fashion was indescribably beautiful in subtlety and sophistication. Yet Mizrahi soon gave it all up to pursue another dream—performing.

Who Wears It

Cindy Crawford, Madonna, Sandra Bernhardt, Natasha Richardson, Liza Minelli, Oprah Winfrey, Uma Thurman

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